General Information
SPKB ID SPKB04505
Signal sequence MELTELLLVVMLLLTARLDPCLP
Length 23
Organism Canis lupus familiaris (Dog) (Canis familiaris)
UniProt ID P42705,
Motif 1..23
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB04505.cif
Physicochemical Information
Molecular weight 2597.26854
Aliphatic index 182.173913
Isoelectric point 3.927538408
Charge (pH=7) -2.059996998
Topological polar surface area 900.2
Aromaticity 0
Average rotatable bonds 3.652173913
Number of hydrogen bond donors 31
Number of hydrogen bond acceptors 33
X logP energy -1.51173
Hydropathy 
Literature Information
Title Identification and cloning of a megakaryocyte growth and development factor that is a ligand for the cytokine receptor Mpl.
DOI 10.1016/0092-8674(94)90450-2,
Publication Year 1994
PubMed ID 8020099,
Patent ID NA,
