SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04504

Signal sequence   MVKFHLLVLIAFTCYTCSD

Length  19

Organism  Aedes aegypti (Yellowfever mosquito) (Culex aegypti)

UniProt ID  P42660,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04504.cif

Structure  SPKB04504.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2204.68844

Aliphatic index  117.8947368

Isoelectric point  7.251146129

Charge (pH=7)   -0.035755005

Topological polar surface area  760.04

Aromaticity  0.157894737

Average rotatable bonds  3.631578947

Number of hydrogen bond donors  29

Number of hydrogen bond acceptors  30

X logP energy  -2.9892

Hydropathy 



Literature Information


Title  An extraovarian protein accumulated in mosquito oocytes is a carboxypeptidase activated in embryos.

DOI  10.1073/pnas.88.23.10821,

Publication Year  1991

PubMed ID  1961751,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.