SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04501

Signal sequence   MDRRRFIKGSMAMAAVCGTSGIASLFSQAAFA

Length  32

Organism  Escherichia coli (strain K12)

UniProt ID  P40120,

Motif  1..32



Activity Information


Pathway  Tat

Natural/Artificial  Natural

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  Tat/SPI



Structure Information


PDB ID  8IOX,

Predicted Structure ID  SPKB04501.cif

Structure  SPKB04501.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3352.95354

Aliphatic index  67.5

Isoelectric point  11.37963925

Charge (pH=7)   2.9361511

Topological polar surface area  1358.68

Aromaticity  0.09375

Average rotatable bonds  3.5

Number of hydrogen bond donors  51

Number of hydrogen bond acceptors  48

X logP energy  -15.81889

Hydropathy 



Literature Information


Title  Comparing the predicted and observed properties of proteins encoded in the genome of Escherichia coli K-12.

DOI  10.1002/elps.1150180807,

Publication Year  1997

PubMed ID  9298646,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.