SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04496

Signal sequence   MENIARKERRRLNETKRFRKVKRSAALVGTAMVGCSVAAPLIQPVQVDA

Length  49

Organism  Enterococcus hirae (strain ATCC 9790 / DSM 20160 / JCM 8729 / LMG 6399 / NBRC 3181 / NCIMB 6459 / NCDO 1258 / NCTC 12367 / WDCM 00089 / R)

UniProt ID  P39046,

Motif  1..49



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04496.cif

Structure  SPKB04496.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  5466.47684

Aliphatic index  89.59183673

Isoelectric point  11.86534751

Charge (pH=7)   6.940578121

Topological polar surface area  2382.4

Aromaticity  0.020408163

Average rotatable bonds  3.857142857

Number of hydrogen bond donors  86

Number of hydrogen bond acceptors  76

X logP energy  -25.61561

Hydropathy 



Literature Information


Title  Cloning and sequence analysis of the muramidase-2 gene from Enterococcus hirae.

DOI  10.1128/jb.174.5.1619-1625.1992,

Publication Year  1992

PubMed ID  1347040,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.