SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04495

Signal sequence   MARLGFGLVSCTFFLAASG

Length  19

Organism  Mesocricetus auratus (Golden hamster)

UniProt ID  P38660,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04495.cif

Structure  SPKB04495.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1948.32834

Aliphatic index  92.63157895

Isoelectric point  8.549912035

Charge (pH=7)   0.936006272

Topological polar surface area  709.71

Aromaticity  0.157894737

Average rotatable bonds  3.210526316

Number of hydrogen bond donors  27

Number of hydrogen bond acceptors  26

X logP energy  -6.08743

Hydropathy 



Literature Information


Title  The gene for a novel protein, a member of the protein disulphide isomerase/form I phosphoinositide-specific phospholipase C family, is amplified in hydroxyurea-resistant cells.

DOI  10.1042/bj2810645,

Publication Year  1992

PubMed ID  1311171,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.