SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04494

Signal sequence   MKHVLTLLALASVFAVSNQALA

Length  22

Organism  Methylophilus methylotrophus (Bacterium W3A1)

UniProt ID  P38540,

Motif  1..22



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Cell membrane

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04494.cif

Structure  SPKB04494.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2297.78444

Aliphatic index  150.9090909

Isoelectric point  9.702001779

Charge (pH=7)   1.088598356

Topological polar surface area  875.99

Aromaticity  0.045454545

Average rotatable bonds  3.409090909

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  31

X logP energy  -6.526

Hydropathy 



Literature Information


Title  The interaction of methanol dehydrogenase and its electron acceptor, cytochrome cL in methylotrophic bacteria.

DOI  10.1016/0167-4838(92)90240-e,

Publication Year  1992

PubMed ID  1311606,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.