SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04486

Signal sequence   MKKVLALVVAAAMGLSSAAFA

Length  21

Organism  Escherichia coli (strain K12)

UniProt ID  P36560,

Motif  1..21



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04486.cif

Structure  SPKB04486.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2049.56114

Aliphatic index  130.4761905

Isoelectric point  10.80537956

Charge (pH=7)   1.997394232

Topological polar surface area  737.82

Aromaticity  0.047619048

Average rotatable bonds  3.238095238

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  28

X logP energy  -5.0372

Hydropathy 



Literature Information


Title  Molecular characterization of the acid-inducible asr gene of Escherichia coli and its role in acid stress response.

DOI  10.1128/JB.185.8.2475-2484.2003,

Publication Year  2003

PubMed ID  12670971,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.