SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04480

Signal sequence   MKLFTGLILCSLVLGVHS

Length  18

Organism  Bos taurus (Bovine)

UniProt ID  P35541,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04480.cif

Structure  SPKB04480.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1931.42534

Aliphatic index  162.2222222

Isoelectric point  8.552755748

Charge (pH=7)   1.026623641

Topological polar surface area  673.41

Aromaticity  0.055555556

Average rotatable bonds  3.555555556

Number of hydrogen bond donors  25

Number of hydrogen bond acceptors  26

X logP energy  -3.1229

Hydropathy 



Literature Information


Title  The complete amino acid sequence of bovine serum amyloid protein A (SAA) and of subspecies of the tissue-deposited amyloid fibril protein A.

DOI  10.1111/j.1365-3083.1992.tb02853.x,

Publication Year  1992

PubMed ID  1738817,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.