SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04475

Signal sequence   MNSVVLQLSVVCLGVSS

Length  17

Organism  Oreochromis mossambicus (Mozambique tilapia) (Tilapia mossambica)

UniProt ID  P34746,

Motif  1..17



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04475.cif

Structure  SPKB04475.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1735.08704

Aliphatic index  154.1176471

Isoelectric point  5.922539791

Charge (pH=7)   -0.063990417

Topological polar surface area  696.02

Aromaticity  0

Average rotatable bonds  3.352941176

Number of hydrogen bond donors  25

Number of hydrogen bond acceptors  26

X logP energy  -8.0022

Hydropathy 



Literature Information


Title  Amino acid sequence of growth hormone isolated from medium of incubated pituitary glands of tilapia (Oreochromis mossambicus).

DOI  10.1016/0016-6480(91)90017-z,

Publication Year  1991

PubMed ID  2019405,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.