SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04474

Signal sequence   MQLTLTLSGSSMQLLLLVSNLLLWENMA

Length  28

Organism  Rattus norvegicus (Rat)

UniProt ID  P34207,

Motif  1..28



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04474.cif

Structure  SPKB04474.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3120.77104

Aliphatic index  153.2142857

Isoelectric point  3.849983241

Charge (pH=7)   -1.000240578

Topological polar surface area  1195.85

Aromaticity  0.035714286

Average rotatable bonds  3.785714286

Number of hydrogen bond donors  41

Number of hydrogen bond acceptors  43

X logP energy  -8.8831

Hydropathy 



Literature Information


Title  Identification and characterization of a new member of the prolactin family, placental lactogen-I variant.

DOI  NA,

Publication Year  1991

PubMed ID  1988439,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.