SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04457

Signal sequence   MSNKNVNVRKSQEITFCLLAGILMFMAMMVAGRAEA

Length  36

Organism  Escherichia coli (strain K12)

UniProt ID  P31697,

Motif  1..36



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  6E14,

Predicted Structure ID  SPKB04457.cif

Structure  SPKB04457.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3976.82064

Aliphatic index  92.22222222

Isoelectric point  9.671299555

Charge (pH=7)   1.938963139

Topological polar surface area  1565.31

Aromaticity  0.055555556

Average rotatable bonds  3.833333333

Number of hydrogen bond donors  55

Number of hydrogen bond acceptors  56

X logP energy  -14.12096

Hydropathy 



Literature Information


Title  FimC, a chaperone-like periplasmic protein of Escherichia coli involved in biogenesis of type 1 fimbriae.

DOI  10.1016/0923-2508(92)90070-5,

Publication Year  1992

PubMed ID  1363735,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.