SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04456

Signal sequence   MDAGASYMRLTGEENWVEVTMDEEKERKGKDVQQGKYRPQVSKPIINRDTNTSFAYKGIFLWGIQITMWILLWTNMCVRA

Length  80

Organism  Caprine arthritis encephalitis virus (strain 63) (CAEV-63)

UniProt ID  P31627,

Motif  1..80



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04456.cif

Structure  SPKB04456.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  9375.80074

Aliphatic index  71.875

Isoelectric point  8.466171005

Charge (pH=7)   0.944108254

Topological polar surface area  3833.9

Aromaticity  0.1125

Average rotatable bonds  3.9375

Number of hydrogen bond donors  135

Number of hydrogen bond acceptors  128

X logP energy  -32.75625

Hydropathy 



Literature Information


Title  Structure and genetic variability of envelope glycoproteins of two antigenic variants of caprine arthritis-encephalitis lentivirus.

DOI  10.1128/JVI.65.11.5744-5750.1991,

Publication Year  1991

PubMed ID  1656067,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.