SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04454

Signal sequence   MKRAHLFVVGVYLLSSCRA

Length  19

Organism  Oryctolagus cuniculus (Rabbit)

UniProt ID  P31235,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04454.cif

Structure  SPKB04454.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2150.63134

Aliphatic index  117.8947368

Isoelectric point  10.45691448

Charge (pH=7)   3.025766604

Topological polar surface area  826.31

Aromaticity  0.105263158

Average rotatable bonds  3.684210526

Number of hydrogen bond donors  32

Number of hydrogen bond acceptors  29

X logP energy  -5.61796

Hydropathy 



Literature Information


Title  Characterization of cardiac calsequestrin.

DOI  10.1021/bi00394a038,

Publication Year  1987

PubMed ID  3427023,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.