SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04453

Signal sequence   MKGPWLVLAALCLSLANLGPRG

Length  22

Organism  Pelophylax lessonae (Pool frog) (Rana lessonae)

UniProt ID  P31231,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04453.cif

Structure  SPKB04453.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2280.81794

Aliphatic index  133.1818182

Isoelectric point  9.833242293

Charge (pH=7)   1.935711238

Topological polar surface area  823.87

Aromaticity  0.045454545

Average rotatable bonds  3.227272727

Number of hydrogen bond donors  29

Number of hydrogen bond acceptors  29

X logP energy  -4.85513

Hydropathy 



Literature Information


Title  Frog brain expresses a 60 KDa Ca2+ binding protein similar to mammalian calreticulin.

DOI  10.1016/0006-291x(91)91584-y,

Publication Year  1991

PubMed ID  2018493,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.