SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04452

Signal sequence   MAPTFQTALFFTIISLSFA

Length  19

Organism  Aquarana catesbeiana (American bullfrog) (Rana catesbeiana)

UniProt ID  P31226,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  6O0D,

Predicted Structure ID  SPKB04452.cif

Structure  SPKB04452.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2106.50734

Aliphatic index  97.89473684

Isoelectric point  6.099999998

Charge (pH=7)   -0.002015701

Topological polar surface area  722.57

Aromaticity  0.210526316

Average rotatable bonds  3.315789474

Number of hydrogen bond donors  25

Number of hydrogen bond acceptors  27

X logP energy  -4.0086

Hydropathy 



Literature Information


Title  Purification and partial sequencing of saxiphilin, a saxitoxin-binding protein from the bullfrog, reveals homology to transferrin.

DOI  NA,

Publication Year  1991

PubMed ID  1869567,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.