SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04449

Signal sequence   MKGACVLVLLWAALLLISGGNC

Length  22

Organism  Felis catus (Cat) (Felis silvestris catus)

UniProt ID  P30438,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04449.cif

Structure  SPKB04449.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2245.82784

Aliphatic index  164.0909091

Isoelectric point  8.229691165

Charge (pH=7)   0.873739834

Topological polar surface area  779.55

Aromaticity  0.045454545

Average rotatable bonds  3.318181818

Number of hydrogen bond donors  29

Number of hydrogen bond acceptors  29

X logP energy  -3.4989

Hydropathy 



Literature Information


Title  Studies on the biochemical structure of the major cat allergen Felis domesticus I.

DOI  10.1016/0161-5890(91)90141-6,

Publication Year  1991

PubMed ID  1712068,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.