SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04446

Signal sequence   MEGVLLFWKYRALFFLVLCSLVLCKVHLSQA

Length  31

Organism  Bombina orientalis (Oriental fire-bellied toad)

UniProt ID  P29007,

Motif  1..31



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04446.cif

Structure  SPKB04446.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3628.49894

Aliphatic index  144.516129

Isoelectric point  8.795310727

Charge (pH=7)   1.965275288

Topological polar surface area  1235.81

Aromaticity  0.161290323

Average rotatable bonds  3.806451613

Number of hydrogen bond donors  46

Number of hydrogen bond acceptors  44

X logP energy  -1.77863

Hydropathy 



Literature Information


Title  Gastrin-releasing peptide (GRP) is not mammalian bombesin. Identification and molecular cloning of a true amphibian GRP distinct from amphibian bombesin in Bombina orientalis.

DOI  NA,

Publication Year  1992

PubMed ID  1551901,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.