SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04443

Signal sequence   MRSLLLLSIVFFVVTVSA

Length  18

Organism  Ascaris suum (Pig roundworm) (Ascaris lumbricoides)

UniProt ID  P28316,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04443.cif

Structure  SPKB04443.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1995.49444

Aliphatic index  178.3333333

Isoelectric point  10.55000222

Charge (pH=7)   0.997980988

Topological polar surface area  700.84

Aromaticity  0.111111111

Average rotatable bonds  3.555555556

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  25

X logP energy  -2.62623

Hydropathy 



Literature Information


Title  Polar zipper sequence in the high-affinity hemoglobin of Ascaris suum: amino acid sequence and structural interpretation.

DOI  10.1073/pnas.89.10.4638,

Publication Year  1992

PubMed ID  1584800,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.