SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04435

Signal sequence   MTAWLGFLAVFLCSWSLRDLVAEA

Length  24

Organism  Gallus gallus (Chicken)

UniProt ID  P26652,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04435.cif

Structure  SPKB04435.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2700.20864

Aliphatic index  122.0833333

Isoelectric point  4.184374695

Charge (pH=7)   -1.061772121

Topological polar surface area  961.39

Aromaticity  0.166666667

Average rotatable bonds  3.458333333

Number of hydrogen bond donors  36

Number of hydrogen bond acceptors  33

X logP energy  -3.61333

Hydropathy 



Literature Information


Title  The 21-kDa protein is a transformation-sensitive metalloproteinase inhibitor of chicken fibroblasts.

DOI  NA,

Publication Year  1991

PubMed ID  1845973,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.