SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04427

Signal sequence   MVKCLLLSFLIIAIFIGVPTAKG

Length  23

Organism  Momordica charantia (Bitter gourd) (Balsam pear)

UniProt ID  P24817,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04427.cif

Structure  SPKB04427.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2448.14984

Aliphatic index  169.5652174

Isoelectric point  9.676237541

Charge (pH=7)   1.935419516

Topological polar surface area  787.23

Aromaticity  0.086956522

Average rotatable bonds  3.47826087

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  30

X logP energy  -0.6471

Hydropathy 



Literature Information


Title  MAP 30: a new inhibitor of HIV-1 infection and replication.

DOI  10.1016/0014-5793(90)80438-o,

Publication Year  1990

PubMed ID  1699801,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.