SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04421

Signal sequence   MGRFIFMSFGLLVVAASLRGTGA

Length  23

Organism  Protobothrops flavoviridis (Habu) (Trimeresurus flavoviridis)

UniProt ID  P23806,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04421.cif

Structure  SPKB04421.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2401.91354

Aliphatic index  106.0869565

Isoelectric point  12.50010931

Charge (pH=7)   1.997977677

Topological polar surface area  888.01

Aromaticity  0.130434783

Average rotatable bonds  3.391304348

Number of hydrogen bond donors  33

Number of hydrogen bond acceptors  31

X logP energy  -6.72816

Hydropathy 



Literature Information


Title  The primary structure of coagulation factor IX/factor X-binding protein isolated from the venom of Trimeresurus flavoviridis. Homology with asialoglycoprotein receptors, proteoglycan core protein, tetranectin, and lymphocyte Fc epsilon receptor for immunoglobulin E.

DOI  NA,

Publication Year  1991

PubMed ID  1831197,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.