SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04415

Signal sequence   MPPSVSRALLLLAGLGCLLPGFLA

Length  24

Organism  Oryctolagus cuniculus (Rabbit)

UniProt ID  P23035,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04415.cif

Structure  SPKB04415.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2410.01714

Aliphatic index  154.5833333

Isoelectric point  8.549912035

Charge (pH=7)   0.936006272

Topological polar surface area  808.61

Aromaticity  0.041666667

Average rotatable bonds  3.041666667

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  30

X logP energy  -3.78053

Hydropathy 



Literature Information


Title  Differential interactions of rabbit plasma alpha-1-antiproteinases S and F with porcine trypsin.

DOI  10.1093/oxfordjournals.jbchem.a122255,

Publication Year  1988

PubMed ID  3259574,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.