SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04412

Signal sequence   MRRLFLSHVLGAWLLLSQLPRELSG

Length  25

Organism  Equus caballus (Horse)

UniProt ID  P22969,

Motif  1..25



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04412.cif

Structure  SPKB04412.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2893.48914

Aliphatic index  140.4

Isoelectric point  12.19913522

Charge (pH=7)   2.090658579

Topological polar surface area  1124.18

Aromaticity  0.08

Average rotatable bonds  3.8

Number of hydrogen bond donors  41

Number of hydrogen bond acceptors  36

X logP energy  -6.57019

Hydropathy 



Literature Information


Title  Affinity purification and sequence determination of equine relaxin.

DOI  10.1210/endo-129-1-375,

Publication Year  1991

PubMed ID  2055195,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.