SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04411

Signal sequence   MRLLTSRATRVPSPSGLLCAVLAMLLLTPSGPLASA

Length  36

Organism  Sus scrofa (Pig)

UniProt ID  P22952,

Motif  1..36



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04411.cif

Structure  SPKB04411.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3665.47244

Aliphatic index  127.5

Isoelectric point  12.19926402

Charge (pH=7)   2.93599965

Topological polar surface area  1394.2

Aromaticity  0

Average rotatable bonds  3.166666667

Number of hydrogen bond donors  51

Number of hydrogen bond acceptors  51

X logP energy  -14.18999

Hydropathy 



Literature Information


Title  Molecular cloning of porcine alveolar macrophage-derived neutrophil chemotactic factors I and II; identification of porcine IL-8 and another intercrine-alpha protein.

DOI  10.1021/bi00158a011,

Publication Year  1992

PubMed ID  1420165,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.