SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04405

Signal sequence   SAIPRGLLLLAGLCCLVFGIMA

Length  22

Organism  Cavia porcellus (Guinea pig)

UniProt ID  P22324,

Motif  <1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04405.cif

Structure  SPKB04405.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2231.84434

Aliphatic index  168.6363636

Isoelectric point  8.231408964

Charge (pH=7)   0.874031556

Topological polar surface area  747.76

Aromaticity  0.045454545

Average rotatable bonds  3.227272727

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  28

X logP energy  -2.82503

Hydropathy 



Literature Information


Title  Molecular cloning and sequence analysis of cDNAs coding for guinea pig alpha 1-antiproteinases S and F and contrapsin.

DOI  NA,

Publication Year  1991

PubMed ID  1985973,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.