SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04402

Signal sequence   MHTLAAVVVLQVCWAAVLWPCPPTHS

Length  26

Organism  Gadus morhua (Atlantic cod)

UniProt ID  P21919,

Motif  1..26



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04402.cif

Structure  SPKB04402.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2830.41964

Aliphatic index  116.1538462

Isoelectric point  7.419162442

Charge (pH=7)   0.055853049

Topological polar surface area  957.17

Aromaticity  0.076923077

Average rotatable bonds  3

Number of hydrogen bond donors  34

Number of hydrogen bond acceptors  36

X logP energy  -4.4535

Hydropathy 



Literature Information


Title  Isolation and characterization of somatolactin, a new protein related to growth hormone and prolactin from Atlantic cod (Gadus morhua) pituitary glands.

DOI  10.1021/bi00220a010,

Publication Year  1991

PubMed ID  1993170,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.