SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04401

Signal sequence   MNKIIILLIILLSFDIISA

Length  19

Organism  Dictyostelium discoideum (Social amoeba)

UniProt ID  P21837,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04401.cif

Structure  SPKB04401.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2143.73954

Aliphatic index  231.0526316

Isoelectric point  6.337367167

Charge (pH=7)   -0.00186425

Topological polar surface area  733.99

Aromaticity  0.052631579

Average rotatable bonds  3.894736842

Number of hydrogen bond donors  25

Number of hydrogen bond acceptors  26

X logP energy  0.1112

Hydropathy 



Literature Information


Title  Membrane-enclosed crystals in Dictyostelium discoideum cells, consisting of developmentally regulated proteins with sequence similarities to known esterases.

DOI  10.1083/jcb.110.3.669,

Publication Year  1990

PubMed ID  2307702,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.