General Information
SPKB ID SPKB04399
Signal sequence MKRVLVLLLALAFGHA
Length 16
Organism Mus musculus (Mouse)
UniProt ID P21614,
Motif 1..16
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB04399.cif
Physicochemical Information
Molecular weight 1752.23764
Aliphatic index 176.875
Isoelectric point 11.65178972
Charge (pH=7) 2.088595045
Topological polar surface area 616.42
Aromaticity 0.0625
Average rotatable bonds 3.625
Number of hydrogen bond donors 22
Number of hydrogen bond acceptors 21
X logP energy -0.74223
Hydropathy 
Literature Information
Title An endocytic pathway essential for renal uptake and activation of the steroid 25-(OH) vitamin D3.
DOI 10.1016/s0092-8674(00)80655-8,
Publication Year 1999
PubMed ID 10052453,
Patent ID NA,
