SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04398

Signal sequence   MLTTTKVFFLLLTTWITWYAIVNPQSRA

Length  28

Organism  Mirabilis jalapa (Garden four-o'clock)

UniProt ID  P21326,

Motif  1..28



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04398.cif

Structure  SPKB04398.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3315.96424

Aliphatic index  111.4285714

Isoelectric point  10.45492462

Charge (pH=7)   1.99683554

Topological polar surface area  1207.75

Aromaticity  0.178571429

Average rotatable bonds  3.607142857

Number of hydrogen bond donors  44

Number of hydrogen bond acceptors  42

X logP energy  -5.93243

Hydropathy 



Literature Information


Title  Reliable sequence determination of ribosome- inactivating proteins by combining electrospray mass spectrometry and Edman degradation.

DOI  10.1002/jms.102,

Publication Year  2001

PubMed ID  11180645,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.