SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04395

Signal sequence   MAPAGLSLGATILCLLAWAGLAAG

Length  24

Organism  Ovis aries (Sheep)

UniProt ID  P20757,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04395.cif

Structure  SPKB04395.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2241.73484

Aliphatic index  142.9166667

Isoelectric point  5.922539791

Charge (pH=7)   -0.063990417

Topological polar surface area  780.08

Aromaticity  0.041666667

Average rotatable bonds  2.833333333

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  29

X logP energy  -5.1775

Hydropathy 



Literature Information


Title  Purification and characterization of ovine angiotensinogen.

DOI  10.1111/j.1432-1033.1986.tb09440.x,

Publication Year  1986

PubMed ID  3081342,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.