SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04393

Signal sequence   MKIYVVATIAWILLQFSAWTTTDA

Length  24

Organism  Saponaria officinalis (Common soapwort) (Lychnis saponaria)

UniProt ID  P20656,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04393.cif

Structure  SPKB04393.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2743.25624

Aliphatic index  122.0833333

Isoelectric point  6.330585692

Charge (pH=7)   -0.002714665

Topological polar surface area  991.99

Aromaticity  0.166666667

Average rotatable bonds  3.5

Number of hydrogen bond donors  36

Number of hydrogen bond acceptors  35

X logP energy  -4.0524

Hydropathy 



Literature Information


Title  Synthesis of saporin gene probes from partial protein sequence data: use of inosine-oligonucleotides, genomic DNA and the polymerase chain reaction.

DOI  10.1007/BF00280379,

Publication Year  1990

PubMed ID  2325629,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.