SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04386

Signal sequence   MKLFPGLLFCSLVLGVSG

Length  18

Organism  Canis lupus familiaris (Dog) (Canis familiaris)

UniProt ID  P19708,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04386.cif

Structure  SPKB04386.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1881.36494

Aliphatic index  140.5555556

Isoelectric point  8.545189979

Charge (pH=7)   0.93571455

Topological polar surface area  615.71

Aromaticity  0.111111111

Average rotatable bonds  3.333333333

Number of hydrogen bond donors  22

Number of hydrogen bond acceptors  24

X logP energy  -2.1353

Hydropathy 



Literature Information


Title  Primary structures of dog and cat amyloid A proteins: comparison to human AA.

DOI  10.1016/0305-0491(89)90030-8,

Publication Year  1989

PubMed ID  2598632,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.