SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04385

Signal sequence   MKLFTGLVFCSLVLGVSS

Length  18

Organism  Felis catus (Cat) (Felis silvestris catus)

UniProt ID  P19707,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  7ZH7,

Predicted Structure ID  SPKB04385.cif

Structure  SPKB04385.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1901.35284

Aliphatic index  135

Isoelectric point  8.545189979

Charge (pH=7)   0.93571455

Topological polar surface area  664.96

Aromaticity  0.111111111

Average rotatable bonds  3.444444444

Number of hydrogen bond donors  25

Number of hydrogen bond acceptors  26

X logP energy  -4.2899

Hydropathy 



Literature Information


Title  Primary structures of dog and cat amyloid A proteins: comparison to human AA.

DOI  10.1016/0305-0491(89)90030-8,

Publication Year  1989

PubMed ID  2598632,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.