SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04382

Signal sequence   MAKNTTNRHYSLRKLKTGTASVAVALTVVGAGLVAGQTVRA

Length  41

Organism  Streptococcus pyogenes

UniProt ID  P19401,

Motif  1..41



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Cell wall

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04382.cif

Structure  SPKB04382.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4212.92744

Aliphatic index  97.56097561

Isoelectric point  12.26643323

Charge (pH=7)   6.087147941

Topological polar surface area  1831.1

Aromaticity  0.024390244

Average rotatable bonds  3.43902439

Number of hydrogen bond donors  67

Number of hydrogen bond acceptors  62

X logP energy  -23.29469

Hydropathy 



Literature Information


Title  Vimentin-cross-reactive epitope of type 12 streptococcal M protein.

DOI  10.1128/iai.57.8.2457-2461.1989,

Publication Year  1989

PubMed ID  2473037,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.