SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04381

Signal sequence   MHVWLILSLASLWTSSIAYS

Length  20

Organism  Ascaris suum (Pig roundworm) (Ascaris lumbricoides)

UniProt ID  P19400,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04381.cif

Structure  SPKB04381.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2278.69404

Aliphatic index  141.5

Isoelectric point  7.542349207

Charge (pH=7)   0.088042976

Topological polar surface area  818.09

Aromaticity  0.15

Average rotatable bonds  3.45

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  30

X logP energy  -3.9606

Hydropathy 



Literature Information


Title  Primary structure of the major pepsin inhibitor from the intestinal parasitic nematode Ascaris suum.

DOI  10.1021/bi00484a003,

Publication Year  1990

PubMed ID  2223768,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.