SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04379

Signal sequence   MKYRYFAKKSFLFISMLAAFKTFA

Length  24

Organism  Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)

UniProt ID  P19250,

Motif  1..24



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04379.cif

Structure  SPKB04379.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2910.57424

Aliphatic index  65.41666667

Isoelectric point  10.90863938

Charge (pH=7)   4.995100024

Topological polar surface area  999.75

Aromaticity  0.291666667

Average rotatable bonds  4

Number of hydrogen bond donors  37

Number of hydrogen bond acceptors  37

X logP energy  -2.47243

Hydropathy 



Literature Information


Title  Amino acid sequence of thermostable direct hemolysin produced by Vibrio parahaemolyticus.

DOI  10.1093/oxfordjournals.jbchem.a121882,

Publication Year  1987

PubMed ID  3571196,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.