SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04376

Signal sequence   MGTRYFLVGFLILLVLGFEVQG

Length  22

Organism  Bos taurus (Bovine)

UniProt ID  P19034,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04376.cif

Structure  SPKB04376.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2473.01424

Aliphatic index  145.9090909

Isoelectric point  6.403313374

Charge (pH=7)   -0.001094303

Topological polar surface area  857.17

Aromaticity  0.181818182

Average rotatable bonds  3.636363636

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  29

X logP energy  -1.44683

Hydropathy 



Literature Information


Title  Primary structure of the bovine analogues to human apolipoproteins CII and CIII. Studies on isoforms and evidence for proteolytic processing.

DOI  10.1111/j.1432-1033.1990.tb19255.x,

Publication Year  1990

PubMed ID  2209608,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.