SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04375

Signal sequence   MRALGAVITLLLWGQLFA

Length  18

Organism  Oryctolagus cuniculus (Rabbit)

UniProt ID  P19007,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04375.cif

Structure  SPKB04375.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1973.45014

Aliphatic index  162.7777778

Isoelectric point  10.55000222

Charge (pH=7)   0.997980988

Topological polar surface area  699.03

Aromaticity  0.111111111

Average rotatable bonds  3.5

Number of hydrogen bond donors  25

Number of hydrogen bond acceptors  23

X logP energy  -1.47563

Hydropathy 



Literature Information


Title  Biosynthesis of rabbit haptoglobin: chemical evidence for a single chain precursor.

DOI  10.1016/0014-5793(83)80623-1,

Publication Year  1983

PubMed ID  6413248,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.