SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04372

Signal sequence   MAVFPNSCLAGCLLIFILLQLPKLDS

Length  26

Organism  Bos taurus (Bovine)

UniProt ID  P18892,

Motif  1..26



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04372.cif

Structure  SPKB04372.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2820.50234

Aliphatic index  153.8461538

Isoelectric point  6.06420051

Charge (pH=7)   -0.125813682

Topological polar surface area  963.2

Aromaticity  0.076923077

Average rotatable bonds  3.461538462

Number of hydrogen bond donors  33

Number of hydrogen bond acceptors  36

X logP energy  -3.8999

Hydropathy 



Literature Information


Title  Cloning and analysis of cDNA encoding bovine butyrophilin, an apical glycoprotein expressed in mammary tissue and secreted in association with the milk-fat globule membrane during lactation.

DOI  NA,

Publication Year  1990

PubMed ID  2387867,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.