SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04371

Signal sequence   MVQRCLVVALLVVVVAAALCSA

Length  22

Organism  Schistocerca gregaria (Desert locust) (Gryllus gregarius)

UniProt ID  P18829,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04371.cif

Structure  SPKB04371.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2228.84164

Aliphatic index  185.9090909

Isoelectric point  8.231408964

Charge (pH=7)   0.874031556

Topological polar surface area  799.64

Aromaticity  0

Average rotatable bonds  3.227272727

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  29

X logP energy  -4.41123

Hydropathy 



Literature Information


Title  Dimer structure of a neuropeptide precursor established: consequences for processing.

DOI  10.1016/0896-6273(89)90074-3,

Publication Year  1989

PubMed ID  2627375,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.