SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04370

Signal sequence   MKGIVLALLLALAGS

Length  15

Organism  Xenopus laevis (African clawed frog)

UniProt ID  P18709,

Motif  1..15



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04370.cif

Structure  SPKB04370.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1469.88934

Aliphatic index  195.3333333

Isoelectric point  9.700002532

Charge (pH=7)   0.997689266

Topological polar surface area  516.97

Aromaticity  0

Average rotatable bonds  3.333333333

Number of hydrogen bond donors  18

Number of hydrogen bond acceptors  19

X logP energy  -1.685

Hydropathy 



Literature Information


Title  Precursor-product relationship between vitellogenin and the yolk proteins as derived from the complete sequence of a Xenopus vitellogenin gene.

DOI  10.1093/nar/15.12.4737,

Publication Year  1987

PubMed ID  3601655,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.