SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04368

Signal sequence   MRLFLSLPVLVVVLSMVLEGPAPAQG

Length  26

Organism  Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)

UniProt ID  P18657,

Motif  1..26



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04368.cif

Structure  SPKB04368.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2737.39804

Aliphatic index  153.4615385

Isoelectric point  6.410149741

Charge (pH=7)   -0.000243889

Topological polar surface area  947.2

Aromaticity  0.038461538

Average rotatable bonds  3.269230769

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  34

X logP energy  -3.97683

Hydropathy 



Literature Information


Title  Homologues of the human C and A apolipoproteins in the Macaca fascicularis (cynomolgus) monkey.

DOI  10.1021/bi00379a037,

Publication Year  1987

PubMed ID  3105581,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.