SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04366

Signal sequence   MANFSESKSMMAVFFMFFLLLLSSSSSSSSS

Length  31

Organism  Catharanthus roseus (Madagascar periwinkle) (Vinca rosea)

UniProt ID  P18417,

Motif  1..31



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04366.cif

Structure  SPKB04366.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3388.92824

Aliphatic index  66.12903226

Isoelectric point  6.408795646

Charge (pH=7)   -0.000535612

Topological polar surface area  1285.49

Aromaticity  0.161290323

Average rotatable bonds  3.64516129

Number of hydrogen bond donors  47

Number of hydrogen bond acceptors  51

X logP energy  -15.1748

Hydropathy 



Literature Information


Title  Coordinated regulation of two indole alkaloid biosynthetic genes from Catharanthus roseus by auxin and elicitors.

DOI  10.1007/BF00047715,

Publication Year  1992

PubMed ID  1600148,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.