SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04365

Signal sequence   MKTLLLTLLVVTIVCLDLAHT

Length  21

Organism  Dendroaspis angusticeps (Eastern green mamba) (Naja angusticeps)

UniProt ID  P18329,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04365.cif

Structure  SPKB04365.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2310.92264

Aliphatic index  194.7619048

Isoelectric point  7.359000943

Charge (pH=7)   0.027070125

Topological polar surface area  818.24

Aromaticity  0

Average rotatable bonds  3.619047619

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  31

X logP energy  -2.7734

Hydropathy 



Literature Information


Title  The complete primary structures of two reduced and S-carboxymethylated Angusticeps-type toxins from Dendroaspis angusticeps (green mamba) venom.

DOI  10.1016/0005-2795(80)90274-3,

Publication Year  1980

PubMed ID  7397227,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.