SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04360

Signal sequence   MPPPALVLLLGFLCHVAIA

Length  19

Organism  Bos taurus (Bovine)

UniProt ID  P17690,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04360.cif

Structure  SPKB04360.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1975.52434

Aliphatic index  169.4736842

Isoelectric point  7.35902981

Charge (pH=7)   0.026918674

Topological polar surface area  589.43

Aromaticity  0.052631579

Average rotatable bonds  2.947368421

Number of hydrogen bond donors  19

Number of hydrogen bond acceptors  23

X logP energy  0.8144

Hydropathy 



Literature Information


Title  Amino acid sequence and location of the disulfide bonds in bovine beta 2 glycoprotein I: the presence of five Sushi domains.

DOI  10.1021/bi00114a012,

Publication Year  1991

PubMed ID  1751487,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.