SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04354

Signal sequence   MQRARPALWAAALIALALLRGPPAARA

Length  27

Organism  Sus scrofa (Pig)

UniProt ID  P16611,

Motif  1..27



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04354.cif

Structure  SPKB04354.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2826.44814

Aliphatic index  123.7037037

Isoelectric point  12.97714556

Charge (pH=7)   3.997971054

Topological polar surface area  1100.03

Aromaticity  0.037037037

Average rotatable bonds  3.185185185

Number of hydrogen bond donors  39

Number of hydrogen bond acceptors  34

X logP energy  -7.57562

Hydropathy 



Literature Information


Title  Identification and NH2-terminal amino acid sequence of three insulin-like growth factor-binding proteins in porcine serum.

DOI  10.1016/0006-291x(91)92056-p,

Publication Year  1991

PubMed ID  1722398,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.