SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04350

Signal sequence   MIIANVIRSFSLTLLIFAALLFRPAAA

Length  27

Organism  Klebsiella pneumoniae

UniProt ID  P15644,

Motif  1..27



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Cell membrane

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04350.cif

Structure  SPKB04350.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2933.63464

Aliphatic index  162.962963

Isoelectric point  12.50010931

Charge (pH=7)   1.997977677

Topological polar surface area  1038.71

Aromaticity  0.111111111

Average rotatable bonds  3.444444444

Number of hydrogen bond donors  37

Number of hydrogen bond acceptors  35

X logP energy  -4.05186

Hydropathy 



Literature Information


Title  Protein secretion by gram-negative bacteria. Characterization of two membrane proteins required for pullulanase secretion by Escherichia coli K-12.

DOI  NA,

Publication Year  1989

PubMed ID  2677007,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.