SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04347

Signal sequence   MALQRTHVLLLLLLLTLLGLGLVQPSYG

Length  28

Organism  Sus scrofa (Pig)

UniProt ID  P15468,

Motif  1..28



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04347.cif

Structure  SPKB04347.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3046.79144

Aliphatic index  191.4285714

Isoelectric point  9.351184298

Charge (pH=7)   1.088039665

Topological polar surface area  1097.91

Aromaticity  0.035714286

Average rotatable bonds  3.571428571

Number of hydrogen bond donors  38

Number of hydrogen bond acceptors  38

X logP energy  -4.01123

Hydropathy 



Literature Information


Title  Primary structure of a ribonuclease from porcine liver, a new member of the ribonuclease superfamily.

DOI  10.1021/bi00451a040,

Publication Year  1989

PubMed ID  2611266,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.