SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04346

Signal sequence   MALQRTQAFLLLLLLTLLGLGLVQPSYG

Length  28

Organism  Bos taurus (Bovine)

UniProt ID  P15467,

Motif  1..28



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04346.cif

Structure  SPKB04346.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3043.74444

Aliphatic index  170.7142857

Isoelectric point  9.348807885

Charge (pH=7)   0.997130574

Topological polar surface area  1112.32

Aromaticity  0.071428571

Average rotatable bonds  3.571428571

Number of hydrogen bond donors  38

Number of hydrogen bond acceptors  38

X logP energy  -5.15103

Hydropathy 



Literature Information


Title  Primary structure of an alkaline ribonuclease from bovine liver.

DOI  10.1093/oxfordjournals.jbchem.a123095,

Publication Year  1990

PubMed ID  2358434,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.