SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04341

Signal sequence   MKLFLLLVISASMLIDGLVNA

Length  21

Organism  Olivierus martensii (Manchurian scorpion) (Mesobuthus martensii)

UniProt ID  P15228,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04341.cif

Structure  SPKB04341.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2261.84984

Aliphatic index  185.7142857

Isoelectric point  6.337367167

Charge (pH=7)   -0.00186425

Topological polar surface area  792.19

Aromaticity  0.047619048

Average rotatable bonds  3.666666667

Number of hydrogen bond donors  27

Number of hydrogen bond acceptors  29

X logP energy  -2.3411

Hydropathy 



Literature Information


Title  Molecular characterization of an anti-epilepsy peptide from the scorpion Buthus martensi Karsch.

DOI  10.1046/j.1432-1327.2001.02132.x,

Publication Year  2001

PubMed ID  11298767,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.